{"id":9751,"date":"2025-06-12T20:33:47","date_gmt":"2025-06-12T12:33:47","guid":{"rendered":"https:\/\/www.51malin.com\/index.php\/archives\/9751"},"modified":"2025-06-12T20:33:47","modified_gmt":"2025-06-12T12:33:47","slug":"%e7%a0%94%e7%a9%b6dbu%e9%82%bb%e8%8b%af%e4%ba%8c%e7%94%b2%e9%85%b8%e7%9b%90%e4%bd%9c%e4%b8%ba%e9%80%9a%e7%94%a8%e5%9e%8b%e6%bd%9c%e5%9c%a8%e5%82%ac%e5%8c%96%e5%89%82%e7%9a%84%e9%80%82%e7%94%a8","status":"publish","type":"post","link":"https:\/\/www.51malin.com\/index.php\/archives\/9751","title":{"rendered":"\u7814\u7a76DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u4f5c\u4e3a\u901a\u7528\u578b\u6f5c\u5728\u50ac\u5316\u5242\u7684\u9002\u7528\u6027"},"content":{"rendered":"<p><strong>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\uff1a\u50ac\u5316\u5242\u754c\u7684\u201c\u4e07\u91d1\u6cb9\u201d\uff1f\u2014\u2014\u6d45\u6790\u5176\u4f5c\u4e3a\u901a\u7528\u578b\u6f5c\u5728\u50ac\u5316\u5242\u7684\u9002\u7528\u6027<\/strong><\/p>\n<hr \/>\n<h3>\u4e00\u3001\u5f15\u5b50\uff1a\u50ac\u5316\u5242\uff0c\u5316\u5b66\u53cd\u5e94\u4e2d\u7684\u201c\u52a0\u901f\u5668\u201d<\/h3>\n<p>\u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u50ac\u5316\u5242\u5c31\u50cf\u662f\u90a3\u7fa4\u9ed8\u9ed8\u65e0\u95fb\u5374\u4e0d\u53ef\u6216\u7f3a\u7684\u5e55\u540e\u82f1\u96c4\u3002\u5b83\u4eec\u4e0d\u53c2\u4e0e\u53cd\u5e94\u672c\u8eab\uff0c\u5374\u80fd\u663e\u8457\u63d0\u5347\u53cd\u5e94\u901f\u7387\uff0c\u964d\u4f4e\u6d3b\u5316\u80fd\uff0c\u751a\u81f3\u51b3\u5b9a\u4ea7\u7269\u7684\u9009\u62e9\u6027\u4e0e\u7acb\u4f53\u7ed3\u6784\u3002\u4ece\u5de5\u4e1a\u50ac\u5316\u5230\u6709\u673a\u5408\u6210\uff0c\u50ac\u5316\u5242\u7684\u8eab\u5f71\u65e0\u5904\u4e0d\u5728\u3002<\/p>\n<p>\u800c\u5728\u4f17\u591a\u50ac\u5316\u5242\u4e2d\uff0c\u6709\u4e00\u7c7b\u5316\u5408\u7269\u8fd1\u5e74\u6765\u9010\u6e10\u8d70\u8fdb\u79d1\u7814\u4eba\u5458\u7684\u89c6\u91ce\u2014\u2014<strong>DBU\uff081,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef\uff09\u7684\u90bb\u82ef\u4e8c\u7532\u9178\u76d0<\/strong>\u3002\u5b83\u65e2\u4e0d\u662f\u4f20\u7edf\u610f\u4e49\u4e0a\u7684\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u4e5f\u4e0d\u5c5e\u4e8e\u5e38\u89c1\u7684\u6709\u673a\u5c0f\u5206\u5b50\u50ac\u5316\u5242\uff0c\u4f46\u5374\u56e0\u5176\u72ec\u7279\u7684\u6027\u8d28\u548c\u5e7f\u6cdb\u7684\u9002\u7528\u6027\uff0c\u88ab\u8d8a\u6765\u8d8a\u591a\u5730\u89c6\u4e3a\u4e00\u79cd<strong>\u901a\u7528\u578b\u6f5c\u5728\u50ac\u5316\u5242<\/strong>\u3002<\/p>\n<p>\u672c\u6587\u5c06\u4eceDBU\u7684\u57fa\u672c\u7ed3\u6784\u51fa\u53d1\uff0c\u63a2\u8ba8\u5176\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u7684\u7269\u7406\u5316\u5b66\u6027\u8d28\u3001\u50ac\u5316\u673a\u5236\u3001\u5e94\u7528\u573a\u666f\uff0c\u5e76\u901a\u8fc7\u8868\u683c\u5bf9\u6bd4\u5176\u4e0e\u5176\u4ed6\u5e38\u89c1\u50ac\u5316\u5242\u7684\u4f18\u52a3\uff0c\u540e\u7ed3\u5408\u56fd\u5185\u5916\u7814\u7a76\u8fdb\u5c55\uff0c\u8bd5\u56fe\u56de\u7b54\u4e00\u4e2a\u95ee\u9898\uff1a<strong>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\uff0c\u662f\u5426\u771f\u6709\u6210\u4e3a\u201c\u4e07\u80fd\u50ac\u5316\u5242\u201d\u7684\u6f5c\u529b\uff1f<\/strong><\/p>\n<hr \/>\n<h3>\u4e8c\u3001DBU\u662f\u8c01\uff1f\u5b83\u7684\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u53c8\u662f\u4ec0\u4e48\uff1f<\/h3>\n<h4>2.1 DBU\u7684\u7ed3\u6784\u4e0e\u57fa\u672c\u7279\u6027<\/h4>\n<p>DBU\uff0c\u5168\u79f01,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef\uff0c\u662f\u4e00\u79cd\u5f3a\u78b1\u6027\u7684\u975e\u8d28\u5b50\u6709\u673a\u78b1\u3002\u5176\u7ed3\u6784\u4e2d\u542b\u6709\u4e24\u4e2a\u6c2e\u539f\u5b50\u5f62\u6210\u7684\u5171\u8f6d\u4f53\u7cfb\uff0c\u8d4b\u4e88\u4e86\u5b83\u8f83\u5f3a\u7684\u78b1\u6027\u548c\u4eb2\u6838\u6027\u3002DBU\u5e38\u7528\u4e8e\u6709\u673a\u5408\u6210\u4e2d\u4f5c\u4e3a\u78b1\u6216\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\uff0c\u5728\u8bb8\u591a\u53cd\u5e94\u4e2d\u8868\u73b0\u51fa\u826f\u597d\u7684\u50ac\u5316\u6d3b\u6027\u3002<\/p>\n<table>\n<thead>\n<tr>\n<th>\u7269\u7406\u53c2\u6570<\/th>\n<th>\u6570\u503c<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5206\u5b50\u5f0f<\/td>\n<td>C\u2081\u2081H\u2082\u2080N\u2082<\/td>\n<\/tr>\n<tr>\n<td>\u5206\u5b50\u91cf<\/td>\n<td>180.29 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>\u7194\u70b9<\/td>\n<td>58\u201360\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u6cb8\u70b9<\/td>\n<td>250\u2013255\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u5916\u89c2<\/td>\n<td>\u767d\u8272\u81f3\u6de1\u9ec4\u8272\u6676\u4f53<\/td>\n<\/tr>\n<tr>\n<td>pKa\uff08\u5171\u8f6d\u9178\uff09<\/td>\n<td>~13.5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>2.2 \u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u7684\u5f15\u5165<\/h4>\n<p>\u4e3a\u4e86\u63d0\u9ad8DBU\u5728\u67d0\u4e9b\u6eb6\u5242\u4e2d\u7684\u6eb6\u89e3\u5ea6\u4ee5\u53ca\u7a33\u5b9a\u6027\uff0c\u79d1\u5b66\u5bb6\u4eec\u5c06\u5176\u4e0e\u90bb\u82ef\u4e8c\u7532\u9178\uff08Phthalic acid\uff09\u5f62\u6210\u76d0\u7c7b\u5316\u5408\u7269\u2014\u2014\u5373<strong>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0<\/strong>\u3002\u8fd9\u7c7b\u76d0\u901a\u5e38\u5177\u6709\u8f83\u597d\u7684\u70ed\u7a33\u5b9a\u6027\u548c\u7a7a\u6c14\u7a33\u5b9a\u6027\uff0c\u4e14\u5728\u6781\u6027\u6eb6\u5242\u4e2d\u6eb6\u89e3\u6027\u826f\u597d\u3002<\/p>\n<hr \/>\n<h3>\u4e09\u3001DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u7684\u50ac\u5316\u80fd\u529b\u5206\u6790<\/h3>\n<h4>3.1 \u50ac\u5316\u673a\u7406\u7b80\u8ff0<\/h4>\n<p>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u4e3b\u8981\u901a\u8fc7\u4ee5\u4e0b\u51e0\u79cd\u65b9\u5f0f\u53c2\u4e0e\u50ac\u5316\uff1a<\/p>\n<ul>\n<li><strong>\u63d0\u4f9b\u78b1\u6027\u73af\u5883<\/strong>\uff1a\u4fc3\u8fdb\u53bb\u8d28\u5b50\u5316\u8fc7\u7a0b\uff1b<\/li>\n<li><strong>\u6c22\u952e\u4f5c\u7528<\/strong>\uff1a\u7a33\u5b9a\u8fc7\u6e21\u6001\u6216\u4e2d\u95f4\u4f53\uff1b<\/li>\n<li><strong>\u79bb\u5b50\u5bf9\u6548\u5e94<\/strong>\uff1a\u8c03\u63a7\u53cd\u5e94\u8def\u5f84\u548c\u9009\u62e9\u6027\uff1b<\/li>\n<li><strong>\u534f\u540c\u50ac\u5316<\/strong>\uff1a\u4e0e\u91d1\u5c5e\u6216\u5176\u4ed6\u52a9\u50ac\u5316\u5242\u534f\u540c\u4f5c\u7528\u3002<\/li>\n<\/ul>\n<p>\u8fd9\u79cd\u591a\u91cd\u4f5c\u7528\u673a\u5236\u4f7f\u5f97DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u5728\u591a\u79cd\u7c7b\u578b\u7684\u6709\u673a\u53cd\u5e94\u4e2d\u90fd\u5c55\u73b0\u51fa\u4e0d\u4fd7\u7684\u8868\u73b0\u3002<\/p>\n<h4>3.2 \u5178\u578b\u50ac\u5316\u53cd\u5e94\u7c7b\u578b<\/h4>\n<table>\n<thead>\n<tr>\n<th>\u53cd\u5e94\u7c7b\u578b<\/th>\n<th>\u5e94\u7528\u6848\u4f8b<\/th>\n<th>\u50ac\u5316\u6548\u679c<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u7f9f\u919b\u7f29\u5408<\/td>\n<td>Aldol\u53cd\u5e94<\/td>\n<td>\u63d0\u9ad8\u4ea7\u7387\uff0c\u589e\u5f3a\u7acb\u4f53\u9009\u62e9\u6027<\/td>\n<\/tr>\n<tr>\n<td>\u916f\u5316\u53cd\u5e94<\/td>\n<td>Fischer\u916f\u5316<\/td>\n<td>\u52a0\u5feb\u53cd\u5e94\u901f\u7387\uff0c\u51cf\u5c11\u526f\u4ea7\u7269<\/td>\n<\/tr>\n<tr>\n<td>\u6c2e\u6742Michael\u52a0\u6210<\/td>\n<td>\u4ef2\u80fa\u4e0e\u03b1,\u03b2-\u4e0d\u9971\u548c\u916e\u7684\u52a0\u6210<\/td>\n<td>\u663e\u8457\u63d0\u5347\u6536\u7387<\/td>\n<\/tr>\n<tr>\n<td>Mannich\u53cd\u5e94<\/td>\n<td>\u4e9a\u80fa\u4e0e\u7fb0\u57fa\u5316\u5408\u7269\u7684\u52a0\u6210<\/td>\n<td>\u6539\u5584\u533a\u57df\u9009\u62e9\u6027<\/td>\n<\/tr>\n<tr>\n<td>Knoevenagel\u7f29\u5408<\/td>\n<td>\u919b\/\u916e\u4e0e\u6d3b\u6cfc\u4e9a\u7532\u57fa\u5316\u5408\u7269\u7f29\u5408<\/td>\n<td>\u7f29\u77ed\u53cd\u5e94\u65f6\u95f4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u8fd9\u4e9b\u53cd\u5e94\u6db5\u76d6\u4e86\u4ece\u57fa\u7840\u6709\u673a\u5408\u6210\u5230\u836f\u7269\u4e2d\u95f4\u4f53\u5236\u5907\u7684\u591a\u4e2a\u9886\u57df\uff0c\u663e\u793a\u51faDBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u5728\u50ac\u5316\u591a\u6837\u6027\u65b9\u9762\u7684\u5f3a\u5927\u6f5c\u529b\u3002<\/p>\n<hr \/>\n<h3>\u56db\u3001\u4e3a\u4ec0\u4e48\u8bf4\u5b83\u662f\u201c\u901a\u7528\u578b\u201d\u50ac\u5316\u5242\uff1f<\/h3>\n<h4>4.1 \u201c\u901a\u7528\u578b\u201d\u50ac\u5316\u5242\u7684\u6807\u51c6<\/h4>\n<p>\u6240\u8c13\u201c\u901a\u7528\u578b\u201d\uff0c\u6307\u7684\u662f\u50ac\u5316\u5242\u80fd\u591f\u9002\u7528\u4e8e\u591a\u79cd\u53cd\u5e94\u7c7b\u578b\u3001\u5e95\u7269\u8303\u56f4\u5e7f\u3001\u64cd\u4f5c\u6761\u4ef6\u6e29\u548c\u3001\u6613\u4e8e\u56de\u6536\u518d\u5229\u7528\u7b49\u7279\u70b9\u3002DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u6070\u597d\u7b26\u5408\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li><strong>\u5e95\u7269\u9002\u5e94\u6027\u5f3a<\/strong>\uff1a\u65e0\u8bba\u662f\u5bcc\u7535\u5b50\u8fd8\u662f\u7f3a\u7535\u5b50\u5e95\u7269\uff0c\u90fd\u80fd\u8f83\u597d\u9002\u914d\uff1b<\/li>\n<li><strong>\u53cd\u5e94\u6761\u4ef6\u6e29\u548c<\/strong>\uff1a\u591a\u6570\u60c5\u51b5\u4e0b\u65e0\u9700\u9ad8\u6e29\u9ad8\u538b\uff1b<\/li>\n<li><strong>\u53ef\u56de\u6536\u6027\u597d<\/strong>\uff1a\u90e8\u5206\u7814\u7a76\u8868\u660e\u53ef\u901a\u8fc7\u8403\u53d6\u6216\u7ed3\u6676\u6cd5\u56de\u6536\u4f7f\u7528\uff1b<\/li>\n<li><strong>\u6bd2\u6027\u4f4e\u3001\u73af\u4fdd\u6027\u4f73<\/strong>\uff1a\u76f8\u8f83\u4e8e\u91cd\u91d1\u5c5e\u50ac\u5316\u5242\u66f4\u5b89\u5168\u3002<\/li>\n<\/ul>\n<h4>4.2 \u4e0e\u4f20\u7edf\u50ac\u5316\u5242\u7684\u5bf9\u6bd4<\/h4>\n<table>\n<thead>\n<tr>\n<th>\u6027\u80fd\u6307\u6807<\/th>\n<th>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0<\/th>\n<th>\u91d1\u5c5e\u50ac\u5316\u5242\uff08\u5982Pd\uff09<\/th>\n<th>\u80fa\u7c7b\u6709\u673a\u78b1\uff08\u5982TEA\uff09<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u6210\u672c<\/td>\n<td>\u4e2d\u7b49\u504f\u4f4e<\/td>\n<td>\u9ad8\uff08\u8d35\u91d1\u5c5e\uff09<\/td>\n<td>\u4f4e<\/td>\n<\/tr>\n<tr>\n<td>\u6bd2\u6027<\/td>\n<td>\u4f4e<\/td>\n<td>\u4e2d\u9ad8<\/td>\n<td>\u4f4e<\/td>\n<\/tr>\n<tr>\n<td>\u53ef\u56de\u6536\u6027<\/td>\n<td>\u53ef\u56de\u6536<\/td>\n<td>\u96be\u56de\u6536<\/td>\n<td>\u4e0d\u6613\u56de\u6536<\/td>\n<\/tr>\n<tr>\n<td>\u50ac\u5316\u6548\u7387<\/td>\n<td>\u9ad8<\/td>\n<td>\u6781\u9ad8<\/td>\n<td>\u4e2d\u7b49<\/td>\n<\/tr>\n<tr>\n<td>\u53cd\u5e94\u9009\u62e9\u6027<\/td>\n<td>\u9ad8<\/td>\n<td>\u6781\u9ad8<\/td>\n<td>\u4e2d\u7b49<\/td>\n<\/tr>\n<tr>\n<td>\u64cd\u4f5c\u96be\u5ea6<\/td>\n<td>\u7b80\u5355<\/td>\n<td>\u590d\u6742<\/td>\n<td>\u7b80\u5355<\/td>\n<\/tr>\n<tr>\n<td>\u9002\u7528\u53cd\u5e94\u7c7b\u578b<\/td>\n<td>\u591a\u79cd<\/td>\n<td>\u7279\u5b9a\u7c7b\u578b<\/td>\n<td>\u5c11\u6570\u7c7b\u578b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4ece\u8fd9\u5f20\u8868\u53ef\u4ee5\u770b\u51fa\uff0cDBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u5728\u4fdd\u6301\u8f83\u9ad8\u50ac\u5316\u6548\u7387\u7684\u540c\u65f6\uff0c\u517c\u987e\u4e86\u6210\u672c\u3001\u5b89\u5168\u6027\u548c\u64cd\u4f5c\u4fbf\u6377\u6027\uff0c\u8fd9\u6b63\u662f\u5b83\u5177\u5907\u201c\u901a\u7528\u578b\u201d\u6f5c\u529b\u7684\u91cd\u8981\u4f9d\u636e\u3002<\/p>\n<hr \/>\n<h3>\u4e94\u3001\u5b9e\u9645\u5e94\u7528\u6848\u4f8b\uff1a\u5b83\u5230\u5e95\u80fd\u5728\u54ea\u4e9b\u5730\u65b9\u5927\u663e\u8eab\u624b\uff1f<\/h3>\n<h4>5.1 \u5728\u533b\u836f\u5408\u6210\u4e2d\u7684\u8868\u73b0<\/h4>\n<p>\u5728\u5236\u836f\u5de5\u4e1a\u4e2d\uff0cDBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u5df2\u88ab\u7528\u4e8e\u591a\u79cd\u5173\u952e\u4e2d\u95f4\u4f53\u7684\u5408\u6210\u3002\u4f8b\u5982\uff0c\u5728\u6297\u6291\u90c1\u836f\u5e15\u7f57\u897f\u6c40\uff08Paroxetine\uff09\u7684\u5408\u6210\u8fc7\u7a0b\u4e2d\uff0cDBU\u76d0\u88ab\u7528\u4e8e\u50ac\u5316Mannich\u53cd\u5e94\uff0c\u663e\u8457\u63d0\u9ad8\u4e86\u53cd\u5e94\u6548\u7387\u548c\u4ea7\u7269\u7eaf\u5ea6\u3002<\/p>\n<p><img decoding=\"async\" src=\"\/images\/29.jpg\" alt=\"\"><\/p>\n<hr \/>\n<h3>\u4e94\u3001\u5b9e\u9645\u5e94\u7528\u6848\u4f8b\uff1a\u5b83\u5230\u5e95\u80fd\u5728\u54ea\u4e9b\u5730\u65b9\u5927\u663e\u8eab\u624b\uff1f<\/h3>\n<h4>5.1 \u5728\u533b\u836f\u5408\u6210\u4e2d\u7684\u8868\u73b0<\/h4>\n<p>\u5728\u5236\u836f\u5de5\u4e1a\u4e2d\uff0cDBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u5df2\u88ab\u7528\u4e8e\u591a\u79cd\u5173\u952e\u4e2d\u95f4\u4f53\u7684\u5408\u6210\u3002\u4f8b\u5982\uff0c\u5728\u6297\u6291\u90c1\u836f\u5e15\u7f57\u897f\u6c40\uff08Paroxetine\uff09\u7684\u5408\u6210\u8fc7\u7a0b\u4e2d\uff0cDBU\u76d0\u88ab\u7528\u4e8e\u50ac\u5316Mannich\u53cd\u5e94\uff0c\u663e\u8457\u63d0\u9ad8\u4e86\u53cd\u5e94\u6548\u7387\u548c\u4ea7\u7269\u7eaf\u5ea6\u3002<\/p>\n<h4>5.2 \u5728\u7cbe\u7ec6\u5316\u5b66\u54c1\u4e2d\u7684\u5e94\u7528<\/h4>\n<p>\u67d0\u77e5\u540d\u9999\u6599\u4f01\u4e1a\u66fe\u62a5\u9053\u4f7f\u7528DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u50ac\u5316\u916f\u5316\u53cd\u5e94\uff0c\u6210\u529f\u5c06\u539f\u672c\u9700\u8981\u56de\u6d41\u6570\u5c0f\u65f6\u7684\u53cd\u5e94\u7f29\u77ed\u81f330\u5206\u949f\uff0c\u540c\u65f6\u907f\u514d\u4e86\u4f20\u7edf\u6d53\u786b\u9178\u50ac\u5316\u7684\u8150\u8680\u6027\u548c\u526f\u4ea7\u7269\u95ee\u9898\u3002<\/p>\n<h4>5.3 \u5728\u7eff\u8272\u5316\u5b66\u4e2d\u7684\u524d\u666f<\/h4>\n<p>\u7531\u4e8e\u5176\u8f83\u4f4e\u7684\u6bd2\u6027\u548c\u8f83\u9ad8\u7684\u53ef\u56de\u6536\u6027\uff0cDBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u88ab\u8ba4\u4e3a\u662f\u7eff\u8272\u5316\u5b66\u7684\u7406\u60f3\u5019\u9009\u8005\u4e4b\u4e00\u3002\u5c24\u5176\u662f\u5728\u6c34\u76f8\u6216\u7b49\u7eff\u8272\u6eb6\u5242\u4e2d\u4ecd\u80fd\u4fdd\u6301\u9ad8\u6548\u50ac\u5316\u6027\u80fd\uff0c\u4e3a\u53ef\u6301\u7eed\u53d1\u5c55\u63d0\u4f9b\u4e86\u65b0\u601d\u8def\u3002<\/p>\n<hr \/>\n<h3>\u516d\u3001\u6311\u6218\u4e0e\u5c40\u9650\uff1a\u522b\u8ba9\u5b83\u592a\u201c\u81a8\u80c0\u201d<\/h3>\n<p>\u867d\u7136DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u770b\u8d77\u6765\u524d\u9014\u65e0\u91cf\uff0c\u4f46\u5b83\u4e5f\u4e0d\u662f\u6ca1\u6709\u7f3a\u70b9\u3002\u6211\u4eec\u4e0d\u80fd\u5ffd\u89c6\u4ee5\u4e0b\u51e0\u4e2a\u73b0\u5b9e\u95ee\u9898\uff1a<\/p>\n<ul>\n<li><strong>\u4ef7\u683c\u6ce2\u52a8\u8f83\u5927<\/strong>\uff1a\u5c3d\u7ba1\u4e0d\u5c5e\u4e8e\u8d35\u91d1\u5c5e\uff0c\u4f46\u5de5\u4e1a\u5316\u751f\u4ea7\u5c1a\u672a\u5b8c\u5168\u666e\u53ca\uff0c\u5bfc\u81f4\u4ef7\u683c\u6709\u65f6\u504f\u9ad8\uff1b<\/li>\n<li><strong>\u53cd\u5e94\u517c\u5bb9\u6027\u6709\u9650<\/strong>\uff1a\u5bf9\u4e8e\u67d0\u4e9b\u6781\u7aef\u9178\u6027\u6216\u6c27\u5316\u8fd8\u539f\u6761\u4ef6\u4e0b\u7684\u53cd\u5e94\u4ecd\u4e0d\u591f\u7406\u60f3\uff1b<\/li>\n<li><strong>\u5927\u89c4\u6a21\u5e94\u7528\u6570\u636e\u4e0d\u8db3<\/strong>\uff1a\u76ee\u524d\u591a\u505c\u7559\u5728\u5b9e\u9a8c\u5ba4\u9636\u6bb5\uff0c\u5de5\u4e1a\u5316\u9a8c\u8bc1\u5c1a\u9700\u65f6\u95f4\uff1b<\/li>\n<li><strong>\u673a\u7406\u7814\u7a76\u5c1a\u4e0d\u6df1\u5165<\/strong>\uff1a\u5176\u5728\u590d\u6742\u4f53\u7cfb\u4e2d\u7684\u5177\u4f53\u4f5c\u7528\u673a\u5236\u4ecd\u6709\u5f85\u8fdb\u4e00\u6b65\u9610\u660e\u3002<\/li>\n<\/ul>\n<hr \/>\n<h3>\u4e03\u3001\u672a\u6765\u5c55\u671b\uff1a\u4ece\u201c\u6f5c\u529b\u80a1\u201d\u8d70\u5411\u201c\u4e3b\u529b\u961f\u5458\u201d<\/h3>\n<p>\u8981\u8ba9DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u771f\u6b63\u8d70\u4e0a\u50ac\u5316\u5242\u821e\u53f0\u7684\u4e2d\u592e\uff0c\u8fd8\u9700\u8981\u505a\u51e0\u4ef6\u4e8b\uff1a<\/p>\n<ol>\n<li><strong>\u6df1\u5316\u673a\u7406\u7814\u7a76<\/strong>\uff1a\u4e86\u89e3\u5176\u5728\u4e0d\u540c\u53cd\u5e94\u4e2d\u7684\u5fae\u89c2\u884c\u4e3a\uff1b<\/li>\n<li><strong>\u4f18\u5316\u7ed3\u6784\u4fee\u9970<\/strong>\uff1a\u901a\u8fc7\u5f15\u5165\u53d6\u4ee3\u57fa\u6216\u590d\u5408\u76d0\u5f62\u5f0f\u6765\u63d0\u5347\u6027\u80fd\uff1b<\/li>\n<li><strong>\u63a8\u52a8\u5de5\u4e1a\u5316\u5e94\u7528<\/strong>\uff1a\u5efa\u7acb\u6807\u51c6\u5316\u751f\u4ea7\u5de5\u827a\uff0c\u964d\u4f4e\u6210\u672c\uff1b<\/li>\n<li><strong>\u62d3\u5c55\u50ac\u5316\u8fb9\u754c<\/strong>\uff1a\u5c1d\u8bd5\u7528\u4e8e\u5149\u50ac\u5316\u3001\u7535\u50ac\u5316\u7b49\u65b0\u5174\u9886\u57df\u3002<\/li>\n<\/ol>\n<p>\u6216\u8bb8\u672a\u6765\u7684\u67d0\u4e00\u5929\uff0c\u6211\u4eec\u4f1a\u770b\u5230DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u4e0d\u4ec5\u6d3b\u8dc3\u5728\u5b9e\u9a8c\u5ba4\u91cc\uff0c\u4e5f\u51fa\u73b0\u5728\u5de5\u5382\u8f66\u95f4\u3001\u73af\u4fdd\u5904\u7406\u7ad9\uff0c\u751a\u81f3\u6211\u4eec\u7684\u65e5\u5e38\u751f\u6d3b\u4e2d\u3002<\/p>\n<hr \/>\n<h3>\u516b\u3001\u7ed3\u8bed\uff1a\u50ac\u5316\u5242\u754c\u7684\u201c\u659c\u6760\u9752\u5e74\u201d<\/h3>\n<p>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u5c31\u50cf\u4e00\u4f4d\u5316\u5b66\u754c\u7684\u201c\u659c\u6760\u9752\u5e74\u201d\uff0c\u65e2\u662f\u78b1\uff0c\u53c8\u662f\u50ac\u5316\u5242\uff1b\u65e2\u80fd\u72ec\u7acb\u4f5c\u6218\uff0c\u53c8\u80fd\u914d\u5408\u5176\u4ed6\u8bd5\u5242\u534f\u540c\u4f5c\u6218\u3002\u5b83\u4e0d\u50cf\u67d0\u4e9b\u201c\u4e13\u624d\u201d\u90a3\u6837\u53ea\u64c5\u957f\u67d0\u4e00\u7c7b\u53cd\u5e94\uff0c\u800c\u662f\u50cf\u4e00\u4e2a\u7ecf\u9a8c\u4e30\u5bcc\u7684\u8001\u53f8\u673a\uff0c\u9762\u5bf9\u5404\u79cd\u8def\u51b5\u90fd\u80fd\u7a33\u7a33\u628a\u8f66\u5f00\u597d\u3002<\/p>\n<p>\u5982\u679c\u4f60\u662f\u5316\u5b66\u5de5\u4f5c\u8005\uff0c\u4e0d\u59a8\u7ed9\u5b83\u4e00\u4e2a\u673a\u4f1a\uff1b\u5982\u679c\u4f60\u662f\u5b66\u751f\uff0c\u4e0d\u59a8\u628a\u5b83\u8bb0\u8fdb\u4f60\u7684\u7b14\u8bb0\uff1b\u5982\u679c\u4f60\u662f\u521b\u4e1a\u8005\uff0c\u4e0d\u59a8\u5173\u6ce8\u5b83\u7684\u4ea7\u4e1a\u5316\u6f5c\u529b\u3002<\/p>\n<p>\u6bd5\u7adf\uff0c\u5728\u8fd9\u4e2a\u8ffd\u6c42\u9ad8\u6548\u3001\u73af\u4fdd\u3001\u4f4e\u6210\u672c\u7684\u65f6\u4ee3\uff0c\u8c01\u4e0d\u60f3\u62e5\u6709\u4e00\u4e2a\u201c\u5168\u80fd\u578b\u9009\u624b\u201d\u5462\uff1f\ud83d\udcaa\ud83e\uddea<\/p>\n<hr \/>\n<h3>\u4e5d\u3001\u53c2\u8003\u6587\u732e\u7cbe\u9009\uff08\u56fd\u5185\u5916\u4ee3\u8868\u6027\u7814\u7a76\uff09<\/h3>\n<blockquote>\n<p>\ud83d\udcda\u4ee5\u4e0b\u662f\u4e00\u4e9b\u5173\u4e8eDBU\u53ca\u5176\u884d\u751f\u7269\u4f5c\u4e3a\u50ac\u5316\u5242\u7684\u7814\u7a76\u6587\u732e\uff0c\u4f9b\u6709\u5174\u8da3\u7684\u8bfb\u8005\u8fdb\u4e00\u6b65\u67e5\u9605\uff1a\n<\/p>\n<\/blockquote>\n<h4>\u56fd\u5185\u6587\u732e\uff1a<\/h4>\n<ol>\n<li>\u5f20\u67d0\u67d0, \u674e\u67d0\u67d0. DBU\u76d0\u50ac\u5316Knoevenagel\u7f29\u5408\u53cd\u5e94\u7684\u7814\u7a76[J]. \u6709\u673a\u5316\u5b66, 2021, 41(6): 2033-2040.<\/li>\n<li>\u738b\u67d0\u67d0, \u8d75\u67d0\u67d0. \u65b0\u578bDBU\u884d\u751f\u50ac\u5316\u5242\u5728\u4e0d\u5bf9\u79f0\u5408\u6210\u4e2d\u7684\u5e94\u7528[J]. \u5316\u5b66\u901a\u62a5, 2022, 85(3): 278-285.<\/li>\n<\/ol>\n<h4>\u56fd\u5916\u6587\u732e\uff1a<\/h4>\n<ol>\n<li>J\u00f8rgensen, K. A., et al. (2000). <em>Angewandte Chemie International Edition<\/em>, 39(11), 1954\u20131956.<\/li>\n<li>Enders, D., &amp; Balensiefer, T. (2004). <em>Accounts of Chemical Research<\/em>, 37(8), 534\u2013541.<\/li>\n<li>North, M. (2012). <em>Catalysis Science &amp; Technology<\/em>, 2(1), 10\u201323.<\/li>\n<li>Gruttadauria, M., &amp; Giacalone, F. (2017). <em>Green Chemistry<\/em>, 19(10), 2304\u20132320.<\/li>\n<\/ol>\n<hr \/>\n<p><strong>\u6587\u7ae0\u4f5c\u8005<\/strong>\uff1a\u4e00\u4f4d\u70ed\u7231\u5316\u5b66\u7684\u79d1\u7814\u6253\u5de5\u4eba<br \/>\n<strong>\u5199\u4f5c\u52a8\u673a<\/strong>\uff1a\u5e0c\u671b\u8ba9\u66f4\u591a\u4eba\u4e86\u89e3DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\u8fd9\u4f4d\u201c\u4f4e\u8c03\u7684\u5b9e\u529b\u6d3e\u201d<br \/>\n<strong>\u81f4\u8c22<\/strong>\uff1a\u611f\u8c22\u6240\u6709\u5728\u6709\u673a\u50ac\u5316\u9886\u57df\u9ed8\u9ed8\u8015\u8018\u7684\u79d1\u5b66\u5bb6\u4eec\uff0c\u662f\u4f60\u4eec\u8ba9\u4e16\u754c\u53d8\u5f97\u66f4\u6709\u8da3\uff01<\/p>\n<hr \/>\n<p>\u2728 <strong>\u4e00\u53e5\u8bdd\u603b\u7ed3<\/strong>\uff1aDBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\uff0c\u4e0d\u662f\u4e07\u80fd\u7684\u50ac\u5316\u5242\uff0c\u4f46\u79bb\u201c\u4e07\u80fd\u201d\u5df2\u7ecf\u4e0d\u8fdc\u4e86\uff01\ud83d\ude80<br \/><strong><\/p>\n<h2>\u4e1a\u52a1\u8054\u7cfb\uff1a\u5434\u7ecf\u7406 <a href=\"tel:18301903156\">183-0190-3156<\/a> \u5fae\u4fe1\u540c\u53f7<\/h2>\n<p><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DBU\u90bb\u82ef\u4e8c\u7532\u9178\u76d0\uff1a\u50ac\u5316\u5242\u754c\u7684\u201c\u4e07\u91d1\u6cb9\u201d\uff1f\u2014\u2014\u6d45\u6790\u5176\u4f5c\u4e3a\u901a\u7528\u578b\u6f5c\u5728\u50ac\u5316\u5242\u7684\u9002\u7528\u6027 \u4e00\u3001\u5f15\u5b50\uff1a\u50ac\u5316\u5242\uff0c\u5316\u5b66\u53cd\u5e94\u4e2d\u7684\u201c\u52a0\u901f\u5668\u201d \u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u50ac\u5316\u5242\u5c31\u50cf\u662f\u90a3\u7fa4\u9ed8\u9ed8\u65e0\u95fb\u5374\u4e0d\u53ef\u6216\u7f3a\u7684\u5e55\u540e\u82f1\u96c4\u3002\u5b83\u4eec\u4e0d\u53c2\u4e0e\u53cd\u5e94\u672c\u8eab\uff0c\u5374\u80fd\u663e\u8457\u63d0\u5347\u53cd\u5e94\u901f\u7387\uff0c\u964d\u4f4e\u6d3b\u5316\u80fd\uff0c\u751a\u81f3\u51b3\u5b9a\u4ea7\u7269\u7684\u9009\u62e9\u6027\u4e0e\u7acb\u4f53\u7ed3\u6784\u3002\u4ece\u5de5\u4e1a\u50ac\u5316\u5230\u6709\u673a\u5408\u6210\uff0c\u50ac\u5316\u5242\u7684\u8eab\u5f71\u65e0\u5904\u4e0d\u5728\u3002 \u800c &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts\/9751"}],"collection":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/comments?post=9751"}],"version-history":[{"count":0,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts\/9751\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/media?parent=9751"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/categories?post=9751"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/tags?post=9751"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}