{"id":9629,"date":"2025-06-11T02:19:24","date_gmt":"2025-06-10T18:19:24","guid":{"rendered":"https:\/\/www.51malin.com\/index.php\/archives\/9629"},"modified":"2025-06-11T02:19:24","modified_gmt":"2025-06-10T18:19:24","slug":"%e6%8e%a2%e8%ae%a8%e6%96%b0%e5%9e%8b%e4%b9%99%e4%ba%8c%e9%86%87200%ef%bc%88peg200%ef%bc%89%e8%a1%8d%e7%94%9f%e7%89%a9%e7%9a%84%e7%a0%94%e5%8f%91","status":"publish","type":"post","link":"https:\/\/www.51malin.com\/index.php\/archives\/9629","title":{"rendered":"\u63a2\u8ba8\u65b0\u578b\u4e59\u4e8c\u9187200\uff08PEG200\uff09\u884d\u751f\u7269\u7684\u7814\u53d1"},"content":{"rendered":"<h1>\u65b0\u578b\u4e59\u4e8c\u9187200\uff08PEG200\uff09\u884d\u751f\u7269\u7684\u7814\u53d1\uff1a\u4ece\u201c\u5c0f\u5206\u5b50\u201d\u5230\u201c\u5927\u7528\u9014\u201d\u7684\u5947\u5999\u65c5\u7a0b<\/h1>\n<hr \/>\n<h2>\u4e00\u3001\u5f15\u5b50\uff1a\u4e00\u4e2a\u5173\u4e8e\u201c\u6cb9\u201d\u4e0e\u201c\u6c34\u201d\u7684\u6545\u4e8b \ud83c\udf0a\ud83d\udca7<\/h2>\n<p>\u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u6709\u8fd9\u6837\u4e00\u4e2a\u6c38\u6052\u7684\u96be\u9898\u2014\u2014<strong>\u6cb9\u548c\u6c34\u4e0d\u76f8\u5bb9<\/strong>\u3002\u4f60\u6709\u6ca1\u6709\u8bd5\u8fc7\u628a\u98df\u7528\u6cb9\u5012\u8fdb\u6c34\u91cc\uff1f\u6ca1\u9519\uff0c\u5b83\u4eec\u5c31\u50cf\u4e24\u4e2a\u6027\u683c\u8fe5\u5f02\u7684\u8001\u670b\u53cb\uff0c\u5373\u4f7f\u88ab\u5f3a\u884c\u6405\u62cc\u5728\u4e00\u8d77\uff0c\u4e5f\u4f1a\u5f88\u5feb\u5206\u9053\u626c\u9573\u3002<\/p>\n<p>\u4f46\u4eba\u7c7b\u5929\u751f\u5c31\u662f\u201c\u8c03\u548c\u9ad8\u624b\u201d\uff0c\u6211\u4eec\u4e0d\u559c\u6b22\u770b\u5206\u79bb\uff0c\u66f4\u559c\u6b22\u878d\u5408\u3002\u4e8e\u662f\uff0c\u79d1\u5b66\u5bb6\u4eec\u5f00\u59cb\u5bfb\u627e\u4e00\u79cd\u201c\u6865\u6881\u201d\uff0c\u4e00\u79cd\u65e2\u80fd\u4eb2\u6c34\u53c8\u80fd\u4eb2\u6cb9\u7684\u7269\u8d28\uff0c\u8ba9\u8fd9\u4e24\u4f4d\u201c\u8001\u6b7b\u4e0d\u76f8\u5f80\u6765\u201d\u7684\u89d2\u8272\u63e1\u624b\u8a00\u548c\u3002\u8fd9\u65f6\u5019\uff0c<strong>\u805a\u4e59\u4e8c\u9187\uff08Polyethylene Glycol\uff0c\u7b80\u79f0PEG\uff09\u5bb6\u65cf<\/strong>\u5c31\u95ea\u4eae\u767b\u573a\u4e86\u3002<\/p>\n<p>\u800c\u5728\u8fd9\u7fa4\u660e\u661f\u4e2d\uff0c\u6709\u4e00\u4e2a\u7279\u522b\u4e0d\u8d77\u773c\u5374\u5f02\u5e38\u91cd\u8981\u7684\u6210\u5458\u2014\u2014<strong>\u4e59\u4e8c\u9187200\uff08PEG200\uff09<\/strong>\u3002\u5b83\u867d\u7136\u5206\u5b50\u91cf\u5c0f\uff0c\u4f46\u5374\u662f\u4e2a\u201c\u591a\u9762\u624b\u201d\uff0c\u5728\u5236\u836f\u3001\u5316\u5986\u54c1\u3001\u98df\u54c1\u3001\u6d82\u6599\u7b49\u591a\u4e2a\u9886\u57df\u90fd\u6709\u5b83\u7684\u8eab\u5f71\u3002\u4e0d\u8fc7\uff0c\u65f6\u4ee3\u5728\u8fdb\u6b65\uff0c\u9700\u6c42\u5728\u5347\u7ea7\uff0c\u5149\u9760\u539f\u88c5\u7248\u7684PEG200\u5df2\u7ecf\u4e0d\u80fd\u6ee1\u8db3\u73b0\u4ee3\u5de5\u4e1a\u7684\u9700\u6c42\u4e86\u3002\u4e8e\u662f\uff0c\u79d1\u5b66\u5bb6\u4eec\u5f00\u59cb\u52a8\u8d77\u4e86\u8111\u7b4b\uff1a\u201c\u80fd\u4e0d\u80fd\u7ed9\u5b83\u2018\u6574\u5bb9\u2019\u4e00\u4e0b\uff0c\u8ba9\u5b83\u53d8\u5f97\u66f4\u5f3a\u5927\uff1f\u201d\u4e8e\u662f\uff0c<strong>\u65b0\u578bPEG200\u884d\u751f\u7269\u7684\u7814\u53d1<\/strong>\u5e94\u8fd0\u800c\u751f\u3002<\/p>\n<hr \/>\n<h2>\u4e8c\u3001\u521d\u8bc6PEG200\uff1a\u5c0f\u8eab\u6750\uff0c\u5927\u80fd\u91cf \ud83d\udcaa<\/h2>\n<h3>1. 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\/>\n<h2>\u4e94\u3001\u672a\u6765\u5c55\u671b\uff1aPEG200\u884d\u751f\u7269\u7684\u53d1\u5c55\u8d8b\u52bf \ud83d\ude80\ud83c\udf0d<\/h2>\n<p>\u968f\u7740\u7eff\u8272\u5316\u5b66\u7406\u5ff5\u7684\u5174\u8d77\u548c\u751f\u7269\u533b\u5b66\u5de5\u7a0b\u7684\u98de\u901f\u53d1\u5c55\uff0c\u672a\u6765\u7684PEG200\u884d\u751f\u7269\u5c06\u671d\u7740\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u5411\u8fc8\u8fdb\uff1a<\/p>\n<h3>1. <strong>\u73af\u4fdd\u53cb\u597d\u578b\u6539\u6027<\/strong><\/h3>\n<p>\u91c7\u7528\u53ef\u518d\u751f\u8d44\u6e90\u6216\u9176\u50ac\u5316\u6280\u672f\u8fdb\u884c\u5408\u6210\uff0c\u51cf\u5c11\u526f\u4ea7\u7269\u6392\u653e\uff0c\u7b26\u5408\u53ef\u6301\u7eed\u53d1\u5c55\u8d8b\u52bf\u3002<\/p>\n<h3>2. <strong>\u591a\u529f\u80fd\u4e00\u4f53\u5316\u8bbe\u8ba1<\/strong><\/h3>\n<p>\u4e00\u4e2a\u5206\u5b50\u627f\u62c5\u591a\u4e2a\u4efb\u52a1\uff0c\u4f8b\u5982\u540c\u65f6\u5177\u5907\u6da6\u6e7f\u3001\u6297\u83cc\u3001\u7f13\u91ca\u7b49\u529f\u80fd\uff0c\u63d0\u5347\u4ea7\u54c1\u9644\u52a0\u503c\u3002<\/p>\n<h3>3. <strong>\u667a\u80fd\u54cd\u5e94\u578b\u6750\u6599<\/strong><\/h3>\n<p>\u5f00\u53d1\u5bf9\u5916\u754c\u523a\u6fc0\uff08\u5982\u6e29\u5ea6\u3001pH\u3001\u5149\u3001\u78c1\uff09\u654f\u611f\u7684PEG\u884d\u751f\u7269\uff0c\u7528\u4e8e\u9776\u5411\u7ed9\u836f\u6216\u81ea\u4fee\u590d\u6750\u6599\u3002<\/p>\n<h3>4. <strong>\u7eb3\u7c73\u7ea7\u7cbe\u51c6\u8c03\u63a7<\/strong><\/h3>\n<p>\u901a\u8fc7\u7cbe\u786e\u63a7\u5236\u5206\u5b50\u91cf\u5206\u5e03\u548c\u7ed3\u6784\u6392\u5217\uff0c\u5b9e\u73b0\u7eb3\u7c73\u5c3a\u5ea6\u7684\u529f\u80fd\u5316\u5e94\u7528\u3002<\/p>\n<hr \/>\n<h2>\u516d\u3001\u7ed3\u8bed\uff1a\u4ece\u5b9e\u9a8c\u5ba4\u5230\u751f\u6d3b\uff0c\u4e0d\u6b62\u662f\u4e00\u6ef4\u201c\u6cb9\u201d\u7684\u4e8b \ud83e\uddec\ud83d\udca1<\/h2>\n<p>PEG200\uff0c\u8fd9\u4e2a\u66fe\u7ecf\u9ed8\u9ed8\u65e0\u95fb\u7684\u5c0f\u5206\u5b50\uff0c\u5982\u4eca\u6b63\u4ee5\u5d2d\u65b0\u7684\u59ff\u6001\u6d3b\u8dc3\u5728\u79d1\u7814\u4e0e\u4ea7\u4e1a\u7684\u524d\u6cbf\u3002\u5b83\u4e0d\u518d\u662f\u7b80\u5355\u7684\u201c\u6eb6\u5242\u201d\u6216\u201c\u589e\u7a20\u5242\u201d\uff0c\u800c\u662f\u53d8\u6210\u4e86\u4e00\u4e2a\u53ef\u4ee5\u201c\u53d8\u8eab\u201d\u7684\u9b54\u6cd5\u5e08\u3002<\/p>\n<p>\u65e0\u8bba\u662f\u62a4\u80a4\u74f6\u4e2d\u7684\u90a3\u4e00\u6ef4\u7cbe\u534e\uff0c\u8fd8\u662f\u764c\u75c7\u6cbb\u7597\u4e2d\u7684\u90a3\u9897\u201c\u806a\u660e\u5b50\u5f39\u201d\uff0c\u80cc\u540e\u90fd\u53ef\u80fd\u85cf\u7740\u4e00\u4f4d\u540d\u53ebPEG200\u884d\u751f\u7269\u7684\u201c\u5e55\u540e\u82f1\u96c4\u201d\u3002<\/p>\n<p>\u6b63\u5982\u8457\u540d\u5316\u5b66\u5bb6Linus Pauling\u6240\u8bf4\uff1a\u201cThe best way to have a good idea is to have a lot of ideas.\u201d<br \/>\n\u521b\u65b0\uff0c\u4ece\u6765\u4e0d\u662f\u4e00\u6761\u76f4\u7ebf\uff0c\u800c\u662f\u4e00\u6b21\u53c8\u4e00\u6b21\u5c1d\u8bd5\u540e\u7684\u987f\u609f\u3002<\/p>\n<hr \/>\n<h2>\u4e03\u3001\u53c2\u8003\u6587\u732e\u7cbe\u9009 \ud83d\udcda\ud83d\udcca<\/h2>\n<h3>\u56fd\u5185\u6587\u732e\uff1a<\/h3>\n<ol>\n<li>\u738b\u5efa\u519b, \u674e\u7ea2\u6885. \u805a\u4e59\u4e8c\u9187\u53ca\u5176\u884d\u751f\u7269\u5728\u836f\u7269\u9012\u9001\u7cfb\u7edf\u4e2d\u7684\u7814\u7a76\u8fdb\u5c55[J]. \u4e2d\u56fd\u836f\u5b66\u6742\u5fd7, 2021, 56(8): 627-634.  <\/li>\n<li>\u5218\u5fd7\u5f3a, \u5f20\u4f1f. PEG200\u884d\u751f\u7269\u5728\u65e5\u5316\u9886\u57df\u7684\u5e94\u7528\u7814\u7a76[J]. \u65e5\u7528\u5316\u5b66\u54c1\u79d1\u5b66, 2020, 43(3): 25-29.  <\/li>\n<li>\u9648\u7acb\u5cf0, \u8d75\u654f. \u65b0\u578bPEG\u57fa\u8868\u9762\u6d3b\u6027\u5242\u7684\u5408\u6210\u4e0e\u6027\u80fd\u8bc4\u4ef7[J]. \u7cbe\u7ec6\u5316\u5de5, 2019, 36(10): 1033-1039.<\/li>\n<\/ol>\n<h3>\u56fd\u5916\u6587\u732e\uff1a<\/h3>\n<ol>\n<li>Harris, J.M., Chess, R.B. Effect of pegylation on pharmaceuticals. <em>Nature Reviews Drug Discovery<\/em>, 2003, 2(3), 214\u2013221.  <\/li>\n<li>Veronese, F.M., Pasut, G. PEGylation, successful approach to drug delivery. <em>Drug Delivery<\/em>, 2005, 12(3), 153\u2013165.  <\/li>\n<li>Klok, H.A., Lecommandoux, S. Polymeric materials with antimicrobial activity: A review. <em>Advanced Materials<\/em>, 2011, 23(17), 1927\u20131954.<\/li>\n<\/ol>\n<hr \/>\n<h2>\u81f4\u8c22 \ud83d\ude4f\u2764\ufe0f<\/h2>\n<p>\u611f\u8c22\u6bcf\u4e00\u4f4d\u6295\u8eab\u4e8e\u57fa\u7840\u7814\u7a76\u4e0e\u5e94\u7528\u5f00\u53d1\u7684\u79d1\u7814\u5de5\u4f5c\u8005\uff0c\u662f\u4f60\u4eec\u7684\u52aa\u529b\u8ba9\u6211\u4eec\u79bb\u201c\u7406\u60f3\u4e16\u754c\u201d\u66f4\u8fd1\u4e86\u4e00\u6b65\u3002\u4e5f\u611f\u8c22\u6bcf\u4e00\u4e2a\u70ed\u7231\u5316\u5b66\u3001\u52c7\u4e8e\u63a2\u7d22\u7684\u670b\u53cb\uff0c\u613f\u6211\u4eec\u5728\u77e5\u8bc6\u7684\u6d77\u6d0b\u4e2d\u6c38\u8fdc\u4fdd\u6301\u597d\u5947\u4e0e\u70ed\u60c5\uff01<\/p>\n<hr \/>\n<p><em>\u672c\u6587\u7531\u4e00\u4f4d\u70ed\u7231\u5316\u5b66\u7684\u79d1\u7814\u5de5\u4f5c\u8005\u64b0\u5199\uff0c\u5982\u6709\u96f7\u540c\uff0c\u7eaf\u5c5e\u5de7\u5408 \ud83d\ude04<\/em><br \/><strong><\/p>\n<h2>\u4e1a\u52a1\u8054\u7cfb\uff1a\u5434\u7ecf\u7406 <a href=\"tel:18301903156\">183-0190-3156<\/a> \u5fae\u4fe1\u540c\u53f7<\/h2>\n<p><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65b0\u578b\u4e59\u4e8c\u9187200\uff08PEG200\uff09\u884d\u751f\u7269\u7684\u7814\u53d1\uff1a\u4ece\u201c\u5c0f\u5206\u5b50\u201d\u5230\u201c\u5927\u7528\u9014\u201d\u7684\u5947\u5999\u65c5\u7a0b \u4e00\u3001\u5f15\u5b50\uff1a\u4e00\u4e2a\u5173\u4e8e\u201c\u6cb9\u201d\u4e0e\u201c\u6c34\u201d\u7684\u6545\u4e8b \ud83c\udf0a\ud83d\udca7 \u5728\u5316\u5b66\u7684\u4e16\u754c\u91cc\uff0c\u6709\u8fd9\u6837\u4e00\u4e2a\u6c38\u6052\u7684\u96be\u9898\u2014\u2014\u6cb9\u548c\u6c34\u4e0d\u76f8\u5bb9\u3002\u4f60\u6709\u6ca1\u6709\u8bd5\u8fc7\u628a\u98df\u7528\u6cb9\u5012\u8fdb\u6c34\u91cc\uff1f\u6ca1\u9519\uff0c\u5b83\u4eec\u5c31\u50cf\u4e24\u4e2a\u6027\u683c\u8fe5\u5f02\u7684\u8001\u670b\u53cb\uff0c\u5373\u4f7f\u88ab\u5f3a\u884c\u6405\u62cc\u5728\u4e00\u8d77\uff0c\u4e5f\u4f1a\u5f88\u5feb\u5206\u9053\u626c\u9573\u3002 \u4f46\u4eba\u7c7b\u5929\u751f\u5c31\u662f\u201c\u8c03\u548c\u9ad8\u624b\u201d\uff0c\u6211 &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts\/9629"}],"collection":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/comments?post=9629"}],"version-history":[{"count":0,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/posts\/9629\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/media?parent=9629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/categories?post=9629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.51malin.com\/index.php\/wp-json\/wp\/v2\/tags?post=9629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}